The ordinary male fertility diagnosis is made by analyzing different semen parameters such as the concentration, mobility, vitality and morphology of spermatozoa. This test is known as SEMINOGRAM. However, different studies have shown that these parameters may vary significantly in the same person. Thus, the results of the test for a male individual can be very different depending on when the seminal analysis is performed.

Obviously, this fact makes the diagnosis and the consequent selection of the most appropriate assisted reproduction technique more difficult and therefore it limits the probability of success.

What is MSOME?

MSOME or “Motile Sperm Organelle Morphology Examination” is a new test that enables the assessment of spermatozoa morphology in real time and with a high level of accuracy. While a conventional semen test is performed with a magnification of 200x to 400x, using this new technology spermatozoa are analyzed at 10,000x.

What are the advantages of MSOME?

Classical methods only give very superficial information about spermatozoa. In contrast, by using MSOME spermatozoa with an altered nucleus with potentially damaged DNA or genetic material can be identified and subsequently be separated from those having a good morphology, which are able to produce good quality embryos. This fact increases the pregnancy rate and reduces the risk of miscarriages dramatically.

MSOME is like a fingerprint

The result of a MSOME test is the most reliable and stable when it comes to analyzing the morphology of spermatozoa. Recent studies show that the obtained result remains invariable for months and therefore provides essential information when assessing sperm quality.

Why is MSOME so useful?

Apart from providing information about the patient’s sperm quality, the MSOME result (percentage of normal spermatozoa) allows us to advise a couple either about a conventional assisted reproduction technique or about IMSI (Intracitoplasmatic sperm injection of oocytes using sperm previously selected using MSOME). In other words, it provides information which was unavailable until recently but which is essential to choose the most appropriate assisted reproduction technique.

Who can have a MSOME test?

Everybody can have a MSOME test done but it is most indicated in men with altered semen or men who have undergone previous assisted reproduction cycles unsuccessfully.

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