Study of sterile couples
Basic sterility study
From the study of the couple and the information provided, our gynaecologists will have all the necessary information at their disposal to diagnose the sterility causes and therefore offer the couple the most suitable treatment to obtain the desired pregnancy. The study of the couple consists of:
At the first appointment our gynaecologists will ask a few questions in order to know the patient’s medical history.
Complete gynaecological examination
To evaluate the female genital tract.
To assess the ovarian function.
Gynaecological ultrasound scan
To identify the position, morphology and volume of the womb and the ovaries.
It also provides information about the ovarian activity. It is advisable to perform this test at the beginning of the menstrual cycle (between third and fifth day).
To evaluate the male factor. It provides information about the quality and the quantity of spermatozoa in the semen sample.
- Extended study of the semen
- Study of the permeability of the fallopian tubes (Hysterosalpingography)
- Study of the ovarian reserve
MSOME, the seminogram of the future
The ordinary male fertility diagnosis is made by analyzing different semen parameters such as the concentration, mobility, vitality and morphology of spermatozoa. This test is known as SEMINOGRAM. However, different studies have shown that these parameters may vary significantly in the same person. Thus, the results of the test for a male individual can be very different depending on when the seminal analysis is performed.
Obviously, this fact makes the diagnosis and the consequent selection of the most appropriate assisted reproduction technique more difficult and therefore it limits the probabilityof success.
What is MSOME?
MSOME or “Motile Sperm Organelle Morphology Examination” is a new test that enables the assessment of spermatozoa morphology in real time and with a high level of accuracy. While a conventional semen test is performed with a magnification of 200x to 400x, using this new technology spermatozoa are analyzed at 10,000x.
Obviously This makes it difficult the diagnosis and choosing the most suitable assisted reproduction technique, and therefore limits the probability of success
Why is MSOME so useful?
Classical methods only give very superficial information about spermatozoa. In contrast, by using MSOME spermatozoa with an altered nucleus with potentially damaged DNA or genetic material can be identified and subsequently be separated from those having a good morphology, which are able to produce good quality embryos. This fact increases the pregnancy rate and reduces the risk of miscarriages dramatically.
What are the advantages of MSOME?
Apart from providing information about the patient’s sperm quality, the MSOME result (percentage of normal spermatozoa) allows us to advise a couple either about a conventional assisted reproduction technique or about IMSI (Intracitoplasmatic sperm injection of oocytes using sperm previously selected using MSOME). In other words, it provides information which was unavailable until recently but which is essential to choose the most appropriate assisted reproduction technique.
Who can have a MSOME test?
Everybody can have a MSOME test done but it is most indicated in men with altered semen or men who have undergone previous assisted reproduction cycles unsuccessfully.